İlker Demirbolat*
Phytotheraphy Research Center, Bezmialem Vakıf University, 34093 Fatih, Istanbul, TURKEY
*Corresponding author. Email: idemirbolat@bezmialem.edu.tr
FULL TEXT: NVEO 2019,Volume 6, Issue 2, Pages 25-31
Abstract
Tension type headache is the most common type of headaches causing mild, moderate and intense pain in the forehead and neck. There are prescription medicines -usually nonsteroidal anti-inflammatory drugs- and herbal remedies to alleviate the pain. As peppermint (Mentha piperita L.) is one of those most used medicinal plants in the world, its essential oil has also a wide range of medical applications like in tension type headache. In this present study a peppermint oil solution preparation in ethanol was developed, and an analytical method was validated to evaluate the stability. GC-FID and GC/MS analyses were used for the standardization, where thymol served as an internal standard. To the best of our knowledge, the peppermint oil preparation was evaluated and validated in the present form for the first time.
Keywords
Peppermint, Mentha piperita L., Validation, Formulation, Stability
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Cite
FULL TEXT: NVEO 2019,Volume 6, Issue 2, Pages 25-31
