Effect Of Particulate Matter On Allergic Response

Abstract

Exacerbation of asthma is linked to PM2.5 pollution (“particulate matter with an aerodynamic diameter of less than 2.5 m”). The purpose of this review is to compile the most recent research on the association between PM exposure, asthama and allergic disorders. Inflammatory and immunological responses, as well as epigenetics, might all play a role in the development of these conditions. In order to give a comprehensive study of the epidemiology of respiratory-related allergic illnesses (including rhinitis and asthma), as well as the influence of air pollution on respiratory allergy-related health, we set out to conduct extensive research (with a focus on particle matter). Long-term exposure to PM2.5, according to our findings, may raise the incidence of asthmatic and allergic disorders or symptoms. Identifying the mechanisms by which PM causes allergic disorders, as well as the factors that increase a person's sensitivity to PM and allergic diseases, such as genetic polymorphisms and crucial exposure windows, is a top focus for researchers.