Prevalence And Antimicrobial Susceptibility Pattern Of enterococccs Species With Special Reference To Vancomycin Resistance enterocccus In Various Clinical Samples

Abstract

Enterococci species exists as normal microbiological flora in oral cavity, intestinal tract and vagina. In recent years Enterococcal infections have emerged as a great therapeutic challenge due to its intrinsic and acquired resistance to Vancomycin. Hence this study aims to characteriseEnterococcus species and its antimicrobial resistant patterns with special reference to Vancomycin in various clinical samples. A descriptive study was conducted in a tertiary care hospital in Chennai. A total of 110 Enterococcus was isolated from 2142 samples, out of which E.faecalis was 59% and E.faecium was 41%. Urine samples showed more Enterococcus than other samples. E.faecium showed more drug resistance than E.faecalis, there was increased resistance to Ampicillin, Ciprofloxacin and Cotrimoxazole (68.8%, 75.5% and 62.2 respectively). VRE among the isolates was 6.36%, in E.faecalis was 4.6% and E.faecium was 8.8%.Enterococcal isolates showed high susceptibility to Teicoplanin and Linezolid. Better infection control measures and judicious use of antimicrobials can reduce the spread of drug resistant Enterococcal strains.