Antimicrobial efficacy of Aqueous Nigella sativa, Aqueous Neem leaf extract, 3% Sodium hypochlorite, and 2% Chlorhexidine against endodontic pathogens belonging to different categories. – An in vitro Study
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Abstract
Aim: To evaluate the antimicrobial efficacy of aqueous Nigella sativa against planktonic forms of endodontic pathogens belonging to different categories.
Materials & Methods: Following irrigating solutions were employed
- Herbal extracts (Aqueous Nigella sativa and Aqueous Neem leaf extract)
- 3% Sodium hypochlorite (NaOCl)
- 2% Chlorhexidine.
An agar culture plate was inoculated with three endodontic pathogens belonging to different categories; Gram-positive cocci Enterococcus faecalis (ATCC 29212), Gram − ve Pseudomonas aeruginosa (ATCC 27853) bacterial and fungal cells Candida albicans (ATCC 10231); zone of inhibition of microorganism was analyzed using well diffusion method.
Conclusion:
Within the limitations of this study, Herbal extracts (Aqueous Nigella sativa and Neem leaf extract) showed better antimicrobial activity.
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