Composition of biologically active compounds, biological and pharmacological activity of the three-part beggarticks (Bidens tripartita L.)

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Rodin M.N , Bokov D.O , Kovaleva T.Yu. , Bobkova N.V , Sergunova E.V , Strelyaeva A.V , Potapova D.A , Evgrafov A.A , Bondar A.A , Marakhova A.I, Zhilkina V.Yu., Kuleshova E.S., Kudashkina N.V., Galiakhmetova E.K, Khasanova S.R, Krasny

Abstract

This review contains the analysis data on phytochemical composition of three-part beggarticks (Bidens tripartita L.) and full biological activity spectrum of the medicinal raw material. Flavonoids, essential oils, phenolcarboxylic acids, polysaccharides, aromatic hydroxy aldehydes, coumarins, tannins, and polyacetylenes are biologically active substances (BAS) of B. tripartita. Various BAS cause multiple pharmacological and biological effects of the plant. Extracts possess antimycotic, antiinflammatory, antithrombotic, antiradical, antioxidant, antibacterial, antidiabetic, antiulcerogenic, and antitumor effects. The extracts are also of analgesic, antipyretic, antiallergic, hepatoprotective, immunostimulating, and hypotensive pharmacological effects. There is also a possibility to inhibit the main enzymes as well as to protect DNA. The B. tripartita medicinal raw material is of great importance for development and making of new drugs.

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