Inhibition Of Human Herpes Virus Type 6&8 Associated With Non-Genetic Autism Spectrum Disorders

Main Article Content

Dr. Fadyia Mahdi Muslim Alameedy

Abstract

Samples were collected on 3-15-2017 until 8-20-2019 from children with autism spectrum, as well as samples were taken from the mother for each child during the study.All samples were diagnosed through RT-PCR by designing primers for each virus as well as for the disease depending on the location of NCBI. The infected children were divided into three groups starting from a year and a half until age 11.5 years and the first group was (23 case ) higher than the rest of the groups, while the ages of mothers were divided into three groups, starting from 25 upto 42 years , noting that the second group had a higher (25 case ) of the virus than the first and third groups (11 and 18 cases), respectively. And with a significant difference at p<0.05). Then both the diagnosed viruses were implanted on the tissue culture cells infective dosage (TCID50/0.1 ml) was (107.6) of virus. and then the viruses were inactivated through the use of a dose-controlled gamma ray(6.864) mSv/h.) and then the cellular changes were observed on the tissue culture cells between 24-48 hours and the study continued for three years.In addition of diagnosis two groups of cytokines, including pro and anti- inflammatory (TNF-alph and IL-37) of human infected.The first study in Iraq is in terms of diagnosing non-inherited autism spectrum disease and due to the associated herpes virus type 6 and 8.

Article Details

Section
Articles