Synthesis of o-tolylphenoxyastatin through a nucleophilic substitution reaction from o-toluoyl chloride and examination of it’s biological activity

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Mamatkulov Nematillo Narzullaevich, Yakubov Lazizxon Ergashxanovich

Abstract

o-Kresol was first carried out in the presence of catalytic iron salts and the composition of the resulting product was determined. The reaction mechanism suggested. Research has been conducted to synthesize the individual substance and a method for the synthesis of o-tolylchloracetate in benzene solution has been developed. Reactions with phenol under different conditions were carried out in order to synthesize a new organic substance. As a result of the research, a new organic substance o-tolylphenoxyacetate was synthesized and its structure was proved by physicochemical methods. This substance has been proven to have biological activity.

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