Effectiveness Of Angioprotector Sulodexide For The Correction Of Vascular Complications In Children With Secondary And Residual Palatal Deformities After Uranoplasty

Abstract

In this article, authors discussed efficiency of angioprotector substance -sulodexidein the correction of vascular
complications in pediatric patients with secondary and residual palatal deformities after uranoplasty.Sulodexideshowed its
anticoagulant effect in the experiments and clinical trials.Moreover,it has an antithrombotic effect, which it implements
mainly through the mechanisms of suppressing the activity of the internal and external pathways of prothrombinase
formation. Activation of fibrinolysis cause of Sulodexide was investigated and confirmed, thereby improving local
microcirculation has also identified. It restores the structure and functional integrity of the endothelium, reducing the
number of desquamated endothelial cells in the peripheral blood, thereby increasing its antithrombogenicity and
thromboresistance.