Comparative Study Of Albumin, Globulin, Lipidprofile, And Ai Between Diabetic Patients And Healthy Participants

Abstract

Diabetes mellitusis known as diabetes, is a metabolic disorder marked by elevated blood sugar concentrations, whileinsulin is the hormone that transfers sugar from the bloodinto the body’s cells, where it can be stored or utilized for energy, so that when we have this condition, the body either doesn't producesufficient amount of insulin or didn't utilize the insulin it does make adequately. Albumin is a family of globular proteins, a number of blood transport proteins are evolutionarily related in the albumin family,globulins are also a group of proteins within the blood. They are produced by the liver and the immune system, wherever albumin makes up more than half of the total protein within the blood, and globulins make up the remainder, whilelipid profileis a pattern of lipids in the blood. A lipid profile usually includes the levels of total cholesterol (TC), high-density lipoprotein (HDL) cholesterol, triglycerides (TG), and the calculated low-density lipoprotein (LDL)cholesterolfurthermore,atherogenic index (AI) (LDL/HDL) can be strong markers for predicting the risk of atherosclerosis and coronary heart disease, The study's goal is to determine the levels of albumin, globulin, TC, TG, HDL-C, LDL-C and AI values in diabetic and healthy individuals, then compares with each other.Consequently in this study, we foundthe levels of albumin (4.24 ± 0.72 to 3.63 ± 0.64 (g/dL) with percentage-14.39%), globulin (3.09 ± 0.63 to 3.31 ± 0.86 (g/dL) with percentage 6.64%), TC (178.90 ± 17.66 to 190.45 ± 17.43 (mg/dL) with percentage 5.32%), TG (155.85 ± 17.06 to 169.15 ± 14.66 (mg/dL) with percentage 8.53%), HDL (49.15 ± 9.35 to 44.68 ± 6.84 (mg/dL) with percentage-9.09%), LDL (96.70 ± 19.56 to 111.95 ± 16.17 (mg/dL) with percentage 15.77%) and AI (2.08 ± 0.73 to 2.56 ± 0.54 with percentage 23.08%) for healthy and diabetic participants respectively, accordinglythis is evidence that the levels of globulin, TC, TG, LDLand AI valuesin diabetic patients higher than healthy participants,but the levels of albumin and HDL in diabetic patients lower than healthy participants, due to the negative effects of diabetes on the heart, blood vessels and other body parts.