Antioxidant Activity of Typha Elephantina Inflorescence Extracts

Abstract

Abnormal levels of reactive nitrogen species and reactive oxygen species lead to cell toxicity disturbing cellular functions, cell survival and alters the cellular components and responsible for oxidative stress-related disorders like cardiovascular diseases, atherosclerosis, diabetes, and cancer. Our current study's objective is to analyze the antioxidant potential of Typha elephantina inflorescence petroleum ether extract (TEPE), chloroform extract (TECE) and methanol extract (TEME). DPPH, ABTS, Nitric oxide and Hydrogen peroxide free radical scavenging assays were conducted for evaluating the antioxidant and free radical scavenging activities. In DPPH assay TEME exhibited 70.97±0.62 percent inhibition at 125µg/ml, whereas standard ascorbic acid exhibited 82.08±1.29% inhibition and IC50 value of standard 15.5 was comparative to the IC50 value of TEME 28.37. In contrast to Petroleum ether and chloroform extract, TEME have significant free radical scavenging tendencies evaluated by mentioned assays. It can be estimated that methanol extract of Typha elephantina has potential free radical scavenging capacity due to the existence of antioxidant compounds and these compounds might serve as prospective source of natural antioxidants, to treat various oxidative stress-related diseases.