A Mechanistic Review of Anti-Obesity Drugs

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Nitheesh Kumar, Narayanan J, Chitra V

Abstract

Obesity is a complicated disease, characterized by an immoderate amount of fat in a human body. Obesity is not alone a point of concern from a cosmetic sector, also affect health problems. The different factor involves in obesity such as genetic factor, environment factor, energy balance dysregulation, metabolic factor. It can be determined by Body Mass Index as well as Body Adiposity Index value and can be controlled by different methods like drugs and nature compounds. This paper reviews on the Food and Drug Administration approved drugs for obesity recently like Semaglutide, bupropion naltrexone, liraglutide, lorcaserin, orlistat, and phentermine topiramate. The natural compounds Salvia officinalis (Lamiaceae), Vitis vinifera (Vitaceae), Arachis hypogaea (Fabaceae), Panax japonicus (Araliaceae).

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