Effect Of Feeding Moringa Oleifera (Moringaceae) Leaves Extract On Rats With Induced Iron Deficiency Anemia

Abstract

Iron deficiency anemia is the most common type of anemia related to malnutrition worldwide. It
represents a major problem in developing countries, especially in Egypt. Moringa oleifera Lam
(Moringaceae) is a highly valued plant, distributed in many countries of the tropics and subtropics. The
aim of this study was conducted to investigate the effect of Moringa oleifera leaves extract on anemic
rats. Thirty five adult female Sprague-Dawley rats, were fed on basal diet for one week for adaptation,
then divided into two main the first main group (n= 7); were fed on basal diet only and served as
negative control group, second main group (n=28); were fed on basal diet deficiency in iron and add
(10 g tannic acid/kg diet) for 3 weeks to induce anemia, then were divided into 4 subgroups, one of
them was fed on basal diet only and kept as positive control group, while the other three subgroup
were fed on basal diet and given orally 1 ml% moringa extract at the concentration of 5,10,15%
respectively. The results indicated that, supplementation with Moringa leaf water extract can help
overcome iron deficiency anemia. Due to improvement in mean hematocrit, hemoglobin, red blood
cells and platelets. As compared to the positive control group. The obtained results revealed an
improvement in their functions and liver profile due to moringa supplementation at the 3 tested levels.
So, Moringa leaf is recommended to anemic patients.