Preparation And Characterization Of Nano Emulsions Of Lipids Components In Total Parenteral Nutrition Of Neonates

Abstract

Parenteral nutrition (PN) is how nutrients are delivered intravenously or directly into the veins in those with Intestinal
Failure. The components within PN are also important, as overfeeding due to the volume of glucose and lipid
components is also related to developing liver dysfunction. Lipid emulsions are oil in water emulsions containing one or
more triacylglycerol oil, a phospholipid emulsifier, and glycerol. Presently, medium-chain triglycerides (derived from
coconut oil), olive oil, Soybean oil, and fish oil are used in lipid emulsion formulas. Being thermodynamically stable
mixtures of two incompatible liquids that function as a cosurfactant and a surfactant, and with a particle size less than
a micron, nano emulsions represent efficient drug carriers.
Numerous drug delivery objectives can be accomplished with the use of nanobiotechnology. It is achieved using
nanoparticles and nanodevices. The duration of a particle's circulatory residence is dictated by its size and capacity to
bind to plasma, which considerably affects therapeutic efficacy. Nanoparticle technology has a plethora of therapeutic
and diagnostic applications.