Biochemical Investigation To Evaluate Chronic Effects Of “Arq-E-Gulab” On Liver Function Test

Main Article Content

Muhammad Osama
Rahila Ikram
Calvin R. Wei
Raheela Saleem
Ghulam Rasool Bhurgri
Fahad Jibran Siyal
Waseem Abbas

Abstract

Natural remedies plays a pivotal role in global health. Natural remedies are often a popular choice in primary health care as they are considered to be low-cost, safe, and easy to access while having a wide variety of medicinal and biological activities. The tradition of consuming natural remedies is very common all over the globe especially in various regions of Pakistan, India, China, Sri Lanka, Thailand, Japan etc. Majority of the population prefers these natural remedies over conventional allopathic drugs to treat minor ailments and disorders. However, these natural products are not 100% free from adverse effects. Usually awareness and reporting culture of adverse events with natural products is very uncommon all over the world. Arq-e-Gulab (AG) is a famous Unani herbal preparation which is commonly known as Rose Water prepared by water-distillation of rose petals of Rosa damascena Mill. flower. It is traditionally used in various ophthalmic preparations to treat eye related allergies and inflammatory states. It is also used in cooking as flavoring agent in preparation of various sweets and meat recipes especially in Asian region. This study aims to investigate the impact of chronic dosing of AG on liver enzymes to evaluate its effect on liver. This study was carried out on albino rabbits. AG was given at two different doses for 60 days for evaluation of biochemical effects. Our study reveals that AG does not possess any hepato-toxic effects.

Article Details

Section
Articles
Author Biographies

Muhammad Osama

Department of Pharmacology, Faculty of Pharmacy, University of Karachi, Karachi, Pakistan

Rahila Ikram

Faculty of Pharmacy, Salim Habib University, Karachi, Pakistan.

Calvin R. Wei

Department of Research and Development, Shing Huei Group, Taipei, Taiwan

Raheela Saleem

College of Pharmacy, Liaquat University of Medical and Health Sciences, Jamshoro, Sindh, Pakistan

Ghulam Rasool Bhurgri

Department of Pharmacology & Therapeutics, Indus Medical College, University of Modern Science, Tando Muhammad Khan, Sindh, Pakistan.

Fahad Jibran Siyal

Department of Pharmacology, Chandka Medical College, Shaheed Mohtarma Benazir Bhutto Medical University, Larkana, Sindh, Pakistan

Waseem Abbas

Institute of Pharmacy, Shaheed Mohtarma Benazir Bhutto Medical University, Larkana, Sindh, Pakistan.