Biochemical Screening Of Unani Herbal Product “Arq-E-Gulab” For Its Chronic Effects On Serum Creatinine Levels

Abstract

Consumption and utilization of natural products as medicines is not uncommon all over the world. Due to their easy accessibility and low cost, people often opt for these herbal remedies to deal with their ailments. Also majority of the people thinks that these herbal remedies are 100 % safe and contain no adverse or side effects. This belief is thought to be developed due to under reporting of adverse events associated with the use of herbal products. There is a dire need to investigate these products for their safety in different disease states and different population and age groups.  Arq-e-Gulab (AG) is a famous Unani herbal product which is commonly known as Rose Water prepared by water-distillation of rose petals of Rosa damascena Mill. flower. It is frequently used in Unani traditional medicine system in treating various eye diseases specially eye allergies and inflammatory conditions. It is also used as a condiment in Asian region in various sweets and meat recipes. This study is planned to evaluate the impact of chronic dosing of AG on serum creatinine to evaluate its effect on kidneys. This study was carried out on albino rabbits. AG was given at two different doses for 60 days for evaluation of biochemical effects. Our study reveals that AG does not possess any nephrotoxic effects.