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2015 VOLUME 2, ISSUE 1, PAGES 22 – 31
Evaluation of transdermal administration of α-cyperone (4,11-selinadien-3-one) isolated from purple nutsedge (Cyperus rotundus) essential oils as a new drug delivery treatment method for lowering cholesterol

Hayfaa A. Al-Shammary1,*, Sahar Malik Al-Saadi2, Fatima J. Anad3

1,3Department of Medical Analysis, Thi-Qar University, Thi-Qar, IRAQ
2Department of Biology, University of Basrah, Basrah , IRAQ

*Corresponding author. Email: Hayfaashamer@yahoo.com; Hayfaashamer@gmail.com

FULL TEXT: NVEO 2015, Volume 2, Issue 1, Pages 22-31

Abstract

The compound α-cyperone (4, 11-selinadien-3-one) isolated from purple nutsedge (Cyperus rotundus) essential oil was investigated for cholesterol lowering effect. In this study, we removed the hair from the back area of the rats, this compound gave us a good result as an alternative drug for lowering serum cholesterol levels via the transdermal route of administration. This compound significantly decreased total serum cholesterol level in rats at p ≤ 0.01.

Keywords

Transdermal administration, cholesterol-lowering drug, Cyperus rotundus, liver

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Cite
Bibtex @ { nveo211755, journal = {Natural Volatiles \& Essential Oils}, issn = {}, eissn = {2148-9637}, address = {Badebio Biotechnology Ltd.}, year = {2015}, volume = {2}, pages = {22 – 31}, doi = {}, title = {Evaluation of transdermal administration of alfa-cyperone (4,11selinadien-3-one) isolated from purple nutsedge (Cyperus rotundus) essential oils as a new drug delivery treatment method for lowering cholesterol}, key = {cite}, author = {Al-Shammary, Hayfaa and Al-Saadi, Sahar and Anad, Fatima} }
APA Al-Shammary, H , Al-Saadi, S , Anad, F . (2015). Evaluation of transdermal administration of alfa-cyperone (4,11selinadien-3-one) isolated from purple nutsedge (Cyperus rotundus) essential oils as a new drug delivery treatment method for lowering cholesterol. Natural Volatiles & Essential Oils, 2 (1), 22-31. Retrieved from http://dergipark.gov.tr/nveo/issue/19768/211755
MLA Al-Shammary, H , Al-Saadi, S , Anad, F . “Evaluation of transdermal administration of alfa-cyperone (4,11selinadien-3-one) isolated from purple nutsedge (Cyperus rotundus) essential oils as a new drug delivery treatment method for lowering cholesterol”. Natural Volatiles & Essential Oils 2 (2015): 22-31 <http://dergipark.gov.tr/nveo/issue/19768/211755>
Chicago Al-Shammary, H , Al-Saadi, S , Anad, F . “Evaluation of transdermal administration of alfa-cyperone (4,11selinadien-3-one) isolated from purple nutsedge (Cyperus rotundus) essential oils as a new drug delivery treatment method for lowering cholesterol”. Natural Volatiles & Essential Oils 2 (2015): 22-31
RIS TY – JOUR T1 – Evaluation of transdermal administration of alfa-cyperone (4,11selinadien-3-one) isolated from purple nutsedge (Cyperus rotundus) essential oils as a new drug delivery treatment method for lowering cholesterol AU – Hayfaa Al-Shammary , Sahar Al-Saadi , Fatima Anad Y1 – 2015 PY – 2015 N1 – DO – T2 – Natural Volatiles & Essential Oils JF – Journal JO – JOR SP – 22 EP – 31 VL – 2 IS – 1 SN – -2148-9637 M3 – UR – Y2 – 2019 ER –
EndNote %0 Natural Volatiles & Essential Oils Evaluation of transdermal administration of alfa-cyperone (4,11selinadien-3-one) isolated from purple nutsedge (Cyperus rotundus) essential oils as a new drug delivery treatment method for lowering cholesterol %A Hayfaa Al-Shammary , Sahar Al-Saadi , Fatima Anad %T Evaluation of transdermal administration of alfa-cyperone (4,11selinadien-3-one) isolated from purple nutsedge (Cyperus rotundus) essential oils as a new drug delivery treatment method for lowering cholesterol %D 2015 %J Natural Volatiles & Essential Oils %P -2148-9637 %V 2 %N 1 %R %U
ISNAD Al-Shammary, Hayfaa , Al-Saadi, Sahar , Anad, Fatima . “Evaluation of transdermal administration of alfa-cyperone (4,11selinadien-3-one) isolated from purple nutsedge (Cyperus rotundus) essential oils as a new drug delivery treatment method for lowering cholesterol”. Natural Volatiles & Essential Oils 2 / 1 (April 2015): 22-31.

FULL TEXT: NVEO 2015, Volume 2, Issue 1, Pages 22-31

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